On-chip Porous Polymer Monoliths for Solid Phase Extraction Using Digital Microfluidics
نویسندگان
چکیده
We present the first use of digital microfluidic techniques to perform on-chip solid phase extraction (SPE). The material used for SPE was a porous polymer monolith with 12-carbon functionality (C12 PPM) which was photopolymerized on-chip and used to desalt a peptide sample prior to nano-electrospray ionization mass spectrometric analysis (nano-ESI-MS). We anticipate this technique may be useful for preparative-scale sample cleanup and concentration.
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تاریخ انتشار 2010